Beta Glucan Fiber ntau

KHOOM PLIG

Poov beta glucan yog dav faib thiab muaj peev xwm loj hauv cov tsiaj txhu thiab nqaij qaib ntau lawm.
Beta glucan yog ib hom macromolecular polysaccharide dav dav hauv cov kab mob, fungi, algae, nroj tsuag thiab tsiaj txhu - Dextran yog ob hom qauv ntawm dextran. Beta glucan kuj yog ib qho tseem ceeb ntawm cov poov xab polysaccharides. Beta glucan feem ntau yog tsim los ntawm (1,3) - D thiab beta (1,6) - D glucans, nrog qhov sib piv ntawm 85: 15. Vim nws txoj kev sib txuas tshwj xeeb thiab intramolecular hydrogen bonding, nws tsim cov qauv kauv molecular. Qhov kev teeb tsa tshwj xeeb no tau yooj yim lees txais los ntawm lub cev tiv thaiv kab mob. Cov kev tshawb fawb tau pom tias nws muaj cov haujlwm lom neeg xws li kev tiv thaiv kab mob, tiv thaiv kab mob, tiv thaiv hluav taws xob, txo cov ntshav siab, txo cov ntshav lipid, tiv thaiv kab mob thiab tiv thaiv qog.
Poov beta glucan tuaj yeem muab rho tawm los ntawm Saccharomyces cerevisiae thiab muaj ntau qhov chaw.

1.Biological kev ua ntawm poov xab glucan

Nyob rau hauv xyoo tas los no, kev ua haujlwm lom neeg ntawm polysaccharides tau tshwm sim tas li. Ntau cov kab mob microbial, nroj tsuag thiab tsiaj polysaccharides muaj lub zog tiv thaiv kab mob thiab muaj kev cuam tshuam tshwj xeeb rau kev tiv thaiv thiab kho cov qog thiab cov kab mob plawv. Nws yog feem ntau ntseeg hais tias lub mechanism ntawm kev txiav txim ntawm polysaccharides yog los ntawm kev sib cuam tshuam nrog lub reticuloendothelial system. Macrophages, lymphocytes thiab leukocytes cuam tshuam rau kev sib txuas ntawm cov tshuaj tiv thaiv kab mob, DNA thiab RNA thiab qib sib piv ntawm cov chaw pw hav zoov thiab cGMP, thiab txhawb cov synthesis ntawm interferon thiab ntxiv.

1.1 Kev tiv thaiv kab mob thiab tiv thaiv qog
Raws li kev tiv thaiv kab mob, cov poov xab beta glucan tuaj yeem ua rau lub cev tiv thaiv kab mob, tso cov cytokines, koom nrog cov tswv tsev tshwj xeeb thiab tsis muaj kev tiv thaiv tshwj xeeb, thiab yog li txhim kho kev tiv thaiv ntawm lub cev. Cov tshuaj tiv thaiv qog nqaij hlav ntawm beta glucan tuaj yeem cuam tshuam nrog nws lub peev xwm los ua kom lub cev tiv thaiv kab mob. Lub immunomodulatory muaj nuj nqi thiab antitumor kev ua ntawm beta glucan nyob ntawm tej yam solubility, molecular hnyav, branching degree thiab coj conformation. Txawm tias qhov sib txawv extraction kuab tshuaj yuav cuam tshuam rau nws txoj haujlwm.

1.2 Avirus thiab tiv thaiv oxidation
Beta glucan kuj muaj cov tshuaj tua kab mob, tshuaj tua kab mob, tshuaj tua kab mob thiab tshuaj tiv thaiv kab mob. S ene rg et al. Kawm txog cov nyhuv antioxidant ntawm beta glucan. Cov txiaj ntsig ntawm cov nas tau pom tias beta glucan tuaj yeem tshem tawm cov kab mob oxidative puas ntawm lub raum thiab zais zis hauv cov nas uas tshwm sim los ntawm nicotine, thiab tseem tshem tawm cov oxidative puas ntawm cov ntaub so ntswg thiab kab mob los ntawm pustulosis.

1.3 Txhawb kev kho qhov txhab
Beta glucan tuaj yeem koom nrog hauv lub cev tiv thaiv ntuj thiab ua kom cov txheej txheem ntawm daim tawv nqaij kho. Hauv vitro cell kab lis kev cai thwmsim pom tias beta glucan tuaj yeem tiv thaiv qhov poob ntawm cov tshuaj tiv thaiv kab mob antioxidant thiab txhawb kev tsim keratinocyte thiab cell proliferation. Lub caij no, beta glucan tuaj yeem siv los ua osmotic inhibitor kom tshem tawm ion toxicity.

1.4 Tiv thaiv kab mob anthrax
Kev ciaj sia ntawm cov nas uas muaj kab mob anthrax tau nce ntxiv tom qab txhaj tshuaj subcutaneous ntawm beta glucan 2.5 zaug, qhia tias Na glucan tuaj yeem muab kev tiv thaiv zoo tiv thaiv kab mob anthrax.

1.5 Txo cov ntshav qab zib
Wang Haibo et al. Pom tau tias beta glucan tuaj yeem tswj cov ntshav qabzib ntau hauv cov nas ntshav qab zib uas raug ntxias los ntawm alloxan. Nyob rau tib lub sijhawm, nws tseem tuaj yeem txhim kho cov piam thaj metabolism hauv cov nas los ntawm kev txo cov ntshav lipid cov ntsiab lus, txhim kho Hemorheology kev ua tau zoo, kho daim siab thiab nephrosis thiab txo lub siab glycogen decomposition.

1.6 Txo cov roj (cholesterol).
Cov qauv tshwj xeeb ntawm beta glucan tuaj yeem txhawb kev tso tawm ntawm lipoproteins thiab fatty acids, thiab decompose cov loj molecules ntawm lipids hauv cov ntshav mus rau hauv me me molecules. Yog li, nws tuaj yeem txhim kho cov ntshav turbidity los ntawm cov ntshav lipids ntau dhau, thiab tuaj yeem txo cov roj cholesterol hauv cov ntshav.

2.Kev siv cov poov xab beta glucan hauv kev yug tsiaj txhu

2.1 poov xab beta glucan tuaj yeem txhim kho lub cev tiv thaiv kab mob ntawm cev xeeb tub sows thiab weaned piglets, txo kev ntxhov siab thiab txhim kho kev tsim khoom.
Ntxiv cov poov xab beta glucan rau kev noj zaub mov ntawm cev xeeb tub sows tuaj yeem ua rau muaj kev nce ntxiv ntawm TG / IL -2 thiab lysozyme hauv cov kua mis, thiab ua kom cov concentration ntawm IgG, IgM, IL-2 thiab GH hauv cov ntshav. ntawm sows, yog li txhawb kev tiv thaiv kev ua haujlwm ntawm sows thiab piglets. Ntxiv cov poov xab glucan rau piglet noj tuaj yeem txhim kho kev tiv thaiv kab mob thiab kev ua haujlwm ntawm piglets, thiab cuam tshuam rau cov hnyuv thiab cov ntshav physiological thiab biochemical indexes ntawm piglets.

2.2 poov xab glucan tuaj yeem tswj cov hnyuv microflora ntawm cov menyuam qaib thiab txo cov kab mob pathogenic xws li Escherichia coli thiab Salmonella hauv cecum.
Cov poov xab glucan tuaj yeem txhim kho kev lom zem thiab lub cev tiv thaiv kab mob ntawm cov broilers, thiab tuaj yeem hloov tau Virginia mycin ua tus neeg sawv cev loj hlob rau broilers txij thaum yug mus txog 38 hnub. Ntxiv 100mg / kg beta glucan rau kev noj zaub mov ntawm cov nteg qe tuaj yeem txhim kho kev tiv thaiv ntawm cov nteg qe, txo cov roj cholesterol cov ntsiab lus ntawm qe qe, txhim kho lub qe zoo, thiab tsis muaj kev cuam tshuam loj rau kev tsim khoom. Cov nyhuv yog qhov zoo dua li kev ntxiv tshuaj tua kab mob.

2.3 beta glucan kuj muaj qee qhov cuam tshuam rau kev tsim khoom, kev tiv thaiv kab mob thiab biochemical indexes ntawm cov menyuam nyuj uas tsis muaj menyuam.
Ntxiv cov poov xab beta glucan rau kev noj zaub mov ntawm cov menyuam mos thaum ntxov tuaj yeem ua rau muaj kev nce ntxiv ntawm cov nyuj txhua hnub, txhim kho cov hnyuv microflora, txhim kho cov hnyuv microorganisms, txhim kho kev hloov pauv hloov pauv thiab kev tiv thaiv kab mob ntawm cov nyuj.

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