1 3 1 6 Beta Glucan

KHOOM PLIG

Khoom taw qhia
Poov xab glucan yog ib hom polysaccharide, -glucan, uas muaj nyob rau hauv cov poov xab cell phab ntsa thiab muaj zog tiv thaiv kab mob. Dextran yog dav pom nyob rau hauv ntau yam fungi thiab nroj tsuag, xws li shiitake nceb, Ganoderma lucidum, thiab oat. Kev ua ntawm glucan sib txawv heev vim muaj ntau qhov chaw thiab cov qauv. Cov kev tshawb fawb tau pom tias tsuas yog glucan tam sim no nyob rau hauv Ganoderma lucidum spores thiab poov xab cell phab ntsa muaj kev tiv thaiv kab mob zoo, hu ua 1 3 1 6 beta glucan.

Cov mis mos molecular (C6H10O6)n, n yog 125-25000
Lub beta- (1,3) cov pob txha pob txha ntawm cov poov xab glucan ua rau nws muaj zog tiv thaiv kab mob. Cov kev tshawb fawb tau pom tias beta -1, 3-1, 6 triple helix qauv zoo dua hauv glucan, cov saw tseem ceeb yog beta (1,3) glucan, sab saw yog beta (1,6) glucan, cov qauv no txawv ntawm cov qauv kab molecular ntawm cov suab thaj, yog ib qho tshwj xeeb triple ultrahelix qauv. Hloov chaw ntawm hydrolyzed rau hauv cov suab thaj yooj yim xws li qabzib hauv plab, cov qauv no khi rau cov receptors tshwj xeeb, thiab dhau los ntawm cov hnyuv epithelium mus rau hauv cov kab mob lymphatic los ntawm endocytosis, thiab los ntawm cov kab mob lymphatic mus rau hauv cov ntshav.

Keeb kwm
Xyoo 1940, Dr. Pillemer tau tshawb pom thiab qhia txog ib yam khoom nyob rau hauv cov phab ntsa ntawm cov poov xab uas muaj zog tiv thaiv kab mob.
Dr. Diluzio ntawm Tulun University pom tias cov tshuaj nyob rau hauv cov poov xab cell phab ntsa los txhawb kev tiv thaiv kab mob yog ib hom polysaccharide --- -glucan.
Cov koom haum tshawb fawb xws li Harvard University, Tulun University, Washington University thiab lub koom haum ntawm radiobiology ntawm US Air Force tau kawm thiab paub tseeb tias cov poov xab -1,3 glucan muaj lub hom phiaj cov nyhuv, uas tuaj yeem coj mus tshem cov co toxins hauv lub cev, thiab nce lub peev xwm phagocytic ntawm macrophages ntau dua 10 npaug. Nws tseem tuaj yeem ua rau tib neeg lub cev tiv thaiv kab mob nrawm nrawm, tsis muaj cov co toxins thiab cov kev mob tshwm sim ntawm cov tshuaj, tiv thaiv kev tshwm sim ntawm ntau yam kab mob.
Xyoo 2009, US Food and Drug Administration (FDA) tau pom zoo cov poov xab -glucan li GRAS (Food Additive Safety Indicator) zaub mov.
Xyoo 2010, Daim Ntawv Tshaj Tawm ntawm Lub Tsev Haujlwm Saib Xyuas Kev Noj Qab Haus Huv ntawm Tib Neeg Tuam Tshoj tau tshaj tawm los ntawm Ministry of Health No.9, 2010, tau txheeb xyuas cov poov xab -glucan ua cov khoom siv tshiab.
Hauv 2011, European Union qhov kev txiav txim siab 2011/762 / EU tso cai rau kev lag luam ntawm poov xab beta glucan ua cov khoom noj tshiab.

Mechanism ntawm kev ua
Cov qauv nquag ntawm -glucan yog polysaccharide uas muaj cov piam thaj hauv cov ntshav. Feem ntau ntawm lawv yog khi los ntawm -1, 3, uas yog txoj kev sib txuas ntawm cov piam thaj. Cov qauv molecular ntawm cov poov xab -glucan yog 1, 3-1, 6, uas yog ib qho tshwj xeeb triple helix qauv nrog kev ua kom muaj zog lom thiab ruaj khov. Nws tuaj yeem qhib macrophages, neutrophils, thiab lwm yam. yog li nws tuaj yeem nce cov ntsiab lus ntawm leukocytes, cytokinins, thiab cov tshuaj tiv thaiv tshwj xeeb. Comprehensively stimulating lub cev tiv thaiv kab mob nyob rau tib lub sij hawm, muaj ib tug zoo heev rov qab nyhuv rau cov puas hlwb. Tom qab ntawd, lub cev tau npaj zoo dua los tawm tsam cov kab mob microbial. -glucan tuaj yeem rov qab muaj peev xwm ntawm cov lymphocytes raug mob los tsim cytokines (L-1) thiab tswj kev tiv thaiv kab mob hauv lub cev.
Ntau qhov kev sim tau pom tias -glucan tuaj yeem txhawb kev tsim cov tshuaj tiv thaiv IgM hauv vivo los txhim kho lub cev tiv thaiv kab mob hauv lub cev. Qhov glucan-activated cell no tuaj yeem ua rau tus tswv tsev tsis muaj kev tiv thaiv tshwj xeeb, yog li nws daim ntawv thov hauv ntau yam kab mob, kab mob, thiab kev raug mob tau nyiam heev.

Yam ntxwv

1. Ua kom muaj zog thiab ntxiv dag zog rau tib neeg lub cev tiv thaiv kab mob
2.Txo oxidation thiab hluav taws xob
3. Pab lub cev cov ntaub so ntswg thiab txhawb qhov txhab kho
4.Txhim kho qhov hnyav, suav nrog kev txaus siab, txo cov suab thaj, nce fiber ntau thiab prebiotics
5.National cov khoom noj tshiab
6.FDA teev nws hauv GRAS
7.Soluble dextran
8.Quasi-kev noj haus fiber ntau muaj nuj nqi
9.High bioactivity
10.Intestinal micro ecological tshuav nyiaj li cas
11. Kev kho tawv nqaij

Daim ntawv thov
Khoom noj khoom haus: nqaij, khoom noj siv mis, biscuits, dej qab zib, kua txiv, thiab lwm yam
Cov khoom noj muaj txiaj ntsig: dej haus, zaub mov hloov hmoov, milkshake, probiotics, kua qhov ncauj, thiab lwm yam
Cosmetic teb: Lotion, cream, daim npog qhov ncauj, essence, thawj kua, toner, thiab lwm yam

Cim npe nrov: 1 3 1 6 beta glucan, Tuam Tshoj, tuam ntxhab, lwm tus muag khoom, Hoobkas, kho, yuav, ua nyob rau hauv Suav teb