Cov txiaj ntsig tshawb fawb ntawm poov xab beta glucan
Beta-glucan yog ib qho nyuaj polysaccharide txuas ua ke hauv ntau qhov sib txuas, suav nrog beta-1,3-glucan, beta-1,4-glucan, thiab beta{{5} }, 6-glucan qab zib. Beta-1,3/-1,6-glucans yog cov nquag nquag, thiab cov molecules nruab nrab no tuaj yeem muab rho tawm los ntawm cov neeg ua mov ci poov xab, Brazil nceb, oats thiab barley. Txawm hais tias ntau qhov kev tshawb fawb soj ntsuam tau ua tiav ntawm glucans los ntawm ntau qhov chaw, nws tsis paub meej tias cov glucans no txawv kiag li. Piv txwv li, beta-glucan muab rho tawm los ntawm Agaricus blazei tuaj yeem nyob hauv tib neeg lub plab thiab tau pom tias txo cov roj cholesterol thiab txo qis insulin thiab ntshav qab zib. Tib lub sijhawm, ntau cov kev tshawb fawb tau pom tias Brazil nceb beta-glucan muaj qee qhov kev tiv thaiv qog thiab tiv thaiv kab mob.
Cov kev tshawb fawb ntawm poov xab beta-glucans sib txawv thiab ntau cov ncauj lus kom ntxaws dua li kev tshawb fawb ntawm lwm qhov chaw ntawm beta-glucans. Qhov tseeb, ntau cov kev tshawb fawb ntxaws tau ua tiav ntawm cov poov xab beta-glucan, qhia nws txoj kev tiv thaiv kab mob tiv thaiv kab mob, hluav taws xob puas, kho hlwb, thiab qog regression. Cov kev tshawb fawb tau meej heev tias lawv txawm pom cov receptors tshwj xeeb rau cov poov xab beta-glucans ntawm kev tiv thaiv kab mob thiab tiv thaiv qog hlwb.
Hauv ib qho ntawm cov kev tshawb fawb no, cov kws tshawb nrhiav pom tias cov poov xab beta -1, 3-glucan khi ncaj qha rau Dectin-1 receptor ntawm macrophages uas muab peb thawj kab ntawm kev tiv thaiv kab mob thiab lwm yam kev noj qab haus huv. hem tiv thaiv. Dectin-1 tau xav tias ua lub luag haujlwm loj hauv phagocytosis ntawm poov xab beta-glucan rau hauv lub cev los ntawm lub plab, thiab ua kom cov macrophages rau kev ua kom huv ntawm cov tshuaj phem. Qhov no ua rau cov poov xab beta-glucan ua lub luag haujlwm tseem ceeb hauv kev pab lub cev tiv thaiv kab mob lossis pab cov macrophages tshem pob taws lossis cov hlwb tuag.
Lwm tus receptor yog CR3 receptor ntawm cov qe ntshav dawb. Cov qe ntshav dawb pab tiv thaiv kab mob thiab qog los ntawm kev khi rau cov tshuaj tiv thaiv nrog rau beta-glucan. Thaum beta-glucans thiab cov tshuaj tiv thaiv khi rau CR3 receptor ntawm cov qe ntshav dawb, lawv rhuav tshem cov kab mob tshwj xeeb thiab cov qog hlwb.
Qhov no muaj qhov cuam tshuam loj heev thaum cov kws kho mob siv cov tshuaj tiv thaiv kab mob monoclonal los tua cov qog hlwb. Thaum siv peb tus kheej cov tshuaj tiv thaiv kab mob (lossis cov tshuaj tiv thaiv ntxiv) ua ke nrog beta-glucan los khi rau qhov chaw receptor, qhov rov qab ntawm cov qog hlwb tuaj yeem pom meej.
Beta-glucans muaj qhov sib txuas zoo sib xws rau tib neeg monocyte receptors los qhib lawv. Lub cev tiv thaiv kab mob, xws li neutrophils, tso tawm leukotrienes uas tiv thaiv kab mob. Beta-glucan tau pom tias ua ib feem hauv qhov kev ua haujlwm no.
Poov xab beta-glucan muaj peev xwm ua tau zoo hauv kev tiv thaiv qhov txhab lwj, tawg puas tsuaj, qog xov tooj cua, thiab kab mob kab mob. Cov ntaub ntawv sim muaj zog heev, thiab kev txiav txim siab tau nkag mus rau qib biochemical.
Kom meej meej, beta-glucans los ntawm oat thiab barley tsis muaj qhov ua tau zoo ib yam li poov xab beta-glucans. Nyob rau tib lub sijhawm, nceb beta-glucan muaj txiaj ntsig zoo sib xws rau cov poov xab beta-glucan, tab sis kev tshawb fawb kuj qhia tau tias nceb tau los ntawm beta-glucan tsis zoo li poov xab-derived beta-glucan.
Dab tsi ntxiv, cov kev tshawb fawb no tau siv cov khoom zoo, siab dawb huv neeg ua mov ci poov xab beta-glucan. Thaum koj xaiv qhov zoo glucan rau koj, ntxiv rau kev sab laj qhov chaw, koj yuav tsum sab laj nws cov ntsiab lus. Yuav cov poov xab beta-glucan cov khoom uas muaj ntau tshaj 80 feem pua beta-1,3-glucan.
